Bovine Neonatal Immunology

Immunology of neonatal gene transfer.

Gene therapy could result in the permanent correction or amelioration of the clinical manifestations of many genetic diseases. However, immune responses to the therapeutic protein pose a significant hurdle for successful gene therapy. Problematic immune responses can include the development of a cytotoxic T lymphocyte (CTL) response that results in the destruction of genetically-modified cells ...

Neonatal (newborn) Bovine Glandular Products

Since the early 1980’s, Biotics Research has been at the forefront of glandular production, reflecting its commitment to research and innovation. Glandulars from Biotics Research are prepared strictly from BSE-free countries and collected under USDA inspection. Most Biotics Research glandular products incorporate tissues from newborn calves, harvested specifically for Biotics Research, to ensur...

Immunology of bovine respiratory syncytial virus infection of cattle.

Bovine respiratory syncytial virus (BRSV) is a respiratory pathogen of cattle that causes severe disease in calves alone and as one of several viruses and bacteria that cause bovine respiratory disease complex. Like human RSV this virus modulates the immune response to avoid stimulation of a vibrant CD8+ T cytotoxic cell response and instead promotes a Th2 response. The Th2 skew sometimes resul...

Incidence of bovine neonatal pancytopenia in 243 farms in Germany

BACKGROUND Several research groups from different European countries have worked on the aetiopathogenesis of bovine neonatal pancytopenia (BNP) and an association between the use of the vaccine PregSure BVD (Pfizer, Germany) and the development of this haemorrhagic disease was confirmed. Because BNP is not a notifiable disease, it is difficult to obtain information on its incidence. Based on ph...

Immunology